| Compound Information | SONAR Target prediction | | Name: | Prazosin hydrochloride | | Unique Identifier: | LOPAC 00137 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C19ClH21N5O4 | | Molecular Weight: | 397.687 g/mol | | X log p: | 12.723 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 72.72 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 9 | | Rotatable Bond Count: | 5 | | Canonical Smiles: | Cl.COc1cc2nc(nc(N)c2cc1OC)N1CCN(=CC1)C(=O)c1occc1 | | Class: | Adrenoceptor | | Action: | Antagonist | | Selectivity: | alpha1 |
| Species: |
4932 |
| Condition: |
BY4741 |
| Replicates: |
8 |
| Raw OD Value: r im |
0.7724±0.0417513 |
| Normalized OD Score: sc h |
1.0005±0.0138786 |
| Z-Score: |
0.0280±0.344647 |
| p-Value: |
0.93119 |
| Z-Factor: |
-8.40188 |
| Fitness Defect: |
0.0713 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 13|E3 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 27.80 Celcius | | Date: | 2005-04-07 YYYY-MM-DD | | Plate CH Control (+): | 0.04800625000000002±0.00227 | | Plate DMSO Control (-): | 0.7375000000000003±0.02694 | | Plate Z-Factor: | 0.9214 |
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| DBLink | Rows returned: 1 | |
| 6603972 |
[4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-5,6-dihydro-3H-pyrazin-1-yl]-(2-furyl)methanone |
| internal high similarity DBLink | Rows returned: 0 | |
| active | Cluster 11747 | Additional Members: 10 | Rows returned: 1 | |
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